Yes, Tadalista Super Active, which contains tadalafil, can interact with antihypertensive drugs. Both tadalafil and antihypertensive Tadalista Super Active medications can lower blood pressure, so using them together can potentially cause a significant drop in blood pressure, leading to symptoms like dizziness, lightheadedness, fainting, or even more serious complications in some cases. It’s crucial to consult with a healthcare professional before combining these medications to ensure safety and appropriate management of potential interactions.